PPCDC

Across TCGA patient cohorts, PPCDC mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPCDC-associated genes across cancer lineages are CD8+ Tcm and MEP. Each is linked with PPCDC in more than 1 cancer types. Because this analysis shows association rather than direction, both PPCDC-to-partner and partner-to-PPCDC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by PPCDC-low versus PPCDC-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPCDC→partner) and Y-score (partner→PPCDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.027	+3.198	.020	.009	3	1
UCEC	MEP →	+0.058	+2.839	<.001	.035	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ Tcm by PPCDC expression — UCEC

Explore this box plot interactively →