PPCDC

Across TCGA cell cohorts, PPCDC RNA expression is significantly associated with the go_rna of many other GO terms, with 3,783 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PPCDC-associated GO terms across cancer lineages are Coenzyme A biosynthetic process, Meiotic chromosome condensation, and Neuroinflammatory response. Each is linked with PPCDC in more than 12 cancer types. Because this analysis shows association rather than direction, both PPCDC-to-partner and partner-to-PPCDC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Coenzyme A biosynthetic process grouped by PPCDC-low versus PPCDC-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPCDC→partner) and Y-score (partner→PPCDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Coenzyme A biosynthetic process →	+0.138	+0.803	<.001	<.001	3	13
PANCREAS	Meiotic chromosome condensation →	+0.107	+0.607	.007	.002	2	9
BREAST	Neuroinflammatory response →	-0.164	-0.797	<.001	.002	3	8
PANCREAS	Cell cycle checkpoint signaling →	+0.065	+0.642	<.001	<.001	3	8
BONE	Nuclear DNA replication →	+0.217	+0.710	<.001	<.001	3	8
LARGE_INTESTINE	Mitotic recombination →	+0.046	+0.462	.002	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,783 associations by consensus.

Coenzyme A biosynthetic process by PPCDC expression — BONE

Explore this box plot interactively →