PPAT

Across TCGA patient cohorts, PPAT RNA expression is significantly associated with the protein abundance of many other proteins, with 17,742 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PPAT-associated proteins across cancer lineages are PAICS_S27, PAICS, and NCAPG_S674. Each is linked with PPAT in more than 9 cancer types. Because this analysis shows association rather than direction, both PPAT-to-partner and partner-to-PPAT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPAT versus PAICS_S27 in LUAD, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPAT→partner) and Y-score (partner→PPAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PAICS_S27 →	+1.333	+0.671	<.001	<.001	3	10
LSCC	PAICS →	+0.582	+0.905	<.001	<.001	3	9
LUAD	NCAPG_S674 →	+0.937	+0.582	<.001	<.001	3	8
LSCC	MCM5 →	+0.576	+0.619	<.001	<.001	3	8
GBM	MCM6 →	+0.627	+0.481	.006	<.001	2	9
UCEC	SMC2 →	+0.518	+0.668	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,742 associations by consensus.

PPAT vs PAICS_S27 — LUAD

Explore this scatter interactively →