PPARGC1B

Across TCGA cell cohorts, PPARGC1B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,148 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PPARGC1B-associated GO terms across cancer lineages are Mitochondrial RNA metabolic process, rRNA metabolic process, and Ribosomal large subunit assembly. Each is linked with PPARGC1B in more than 15 cancer types. Because this analysis shows association rather than direction, both PPARGC1B-to-partner and partner-to-PPARGC1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial RNA metabolic process grouped by PPARGC1B-low versus PPARGC1B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PPARGC1B→partner) and Y-score (partner→PPARGC1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Mitochondrial RNA metabolic process →	+0.116	+1.312	.001	<.001	3	16
BONE	rRNA metabolic process →	+0.143	+1.350	<.001	<.001	3	16
BONE	Ribosomal large subunit assembly →	+0.142	+1.143	<.001	<.001	3	16
BONE	Ribosomal small subunit biogenesis →	+0.137	+1.377	<.001	<.001	3	16
BLOOD_Myeloma	rRNA processing →	+0.106	+0.965	<.001	<.001	3	16
BLOOD_Myeloma	Ribosome assembly →	+0.103	+0.821	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,148 associations by consensus.

Mitochondrial RNA metabolic process by PPARGC1B expression — BONE

Explore this box plot interactively →