PPARG

Across TCGA patient cohorts, PPARG RNA expression is significantly associated with the protein abundance of many other proteins, with 18,838 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPARG-associated proteins across cancer lineages are PPARG_S112, KANK2, and PLCD1. Each is linked with PPARG in more than 6 cancer types. Because this analysis shows association rather than direction, both PPARG-to-partner and partner-to-PPARG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPARG versus PPARG_S112 in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PPARG→partner) and Y-score (partner→PPARG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PPARG_S112 →	+0.697	+1.044	<.001	<.001	3	7
BRCA	KANK2 →	+0.433	+0.706	<.001	<.001	3	6
BRCA	PLCD1 →	+0.361	+0.773	.001	.002	3	5
PDAC	SPTBN1 →	+0.286	+0.978	<.001	<.001	3	5
GBM	EHD4 →	+0.343	+0.781	<.001	<.001	3	5
HNSC	EPB41L2 →	+0.417	+0.636	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,838 associations by consensus.

PPARG vs PPARG_S112 — LSCC

Explore this scatter interactively →