PPARG

Across TCGA patient cohorts, PPARG protein abundance is significantly associated with the RNA expression of many other genes, with 117 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PPARG-associated genes across cancer lineages are HMOX1, RASIP1, and RASAL1. Each is linked with PPARG in more than 1 cancer types. Because this analysis shows association rather than direction, both PPARG-to-partner and partner-to-PPARG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPARG versus HMOX1 in BRCA, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPARG→partner) and Y-score (partner→PPARG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HMOX1 →	+1.660	+1.031	.001	.002	3	1
BRCA	RASIP1 →	+0.947	+0.743	.001	.004	3	1
BRCA	RASAL1 →	+2.346	+1.152	<.001	.007	3	1
BRCA	FNDC4 →	+1.303	+0.930	<.001	<.001	3	1
BRCA	GJA9 →	-0.128	-0.948	<.001	.007	3	1
BRCA	EMILIN2 →	+1.271	+0.765	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 117 associations by consensus.

PPARG vs HMOX1 — BRCA

Explore this scatter interactively →