POU4F3

Across TCGA patient cohorts, POU4F3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,757 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POU4F3-associated genes across cancer lineages are RHBDD2, COG5, and CRCP. Each is linked with POU4F3 in more than 4 cancer types. Because this analysis shows association rather than direction, both POU4F3-to-partner and partner-to-POU4F3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POU4F3 versus RHBDD2 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU4F3→partner) and Y-score (partner→POU4F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RHBDD2 →	+0.723	+0.287	.003	.001	3	5
HNSC	COG5 →	+0.634	+0.403	<.001	<.001	3	5
LSCC	CRCP →	+0.486	+0.345	<.001	.001	3	4
GBM	MTPN →	+0.368	+0.315	<.001	<.001	3	4
HNSC	PNPLA8 →	+0.567	+0.229	<.001	<.001	3	4
HNSC	LMTK2 →	+0.610	+0.213	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,757 associations by consensus.

POU4F3 vs RHBDD2 — OV

Explore this scatter interactively →