POU4F3

Across TCGA cell cohorts, POU4F3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,648 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POU4F3-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Macroautophagy. Each is linked with POU4F3 in more than 10 cancer types. Because this analysis shows association rather than direction, both POU4F3-to-partner and partner-to-POU4F3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Process utilizing autophagic mechanism grouped by POU4F3-low versus POU4F3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU4F3→partner) and Y-score (partner→POU4F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Process utilizing autophagic mechanism →	+0.087	+0.132	<.001	.003	3	11
STOMACH	Autophagy →	+0.087	+0.132	<.001	.003	3	11
STOMACH	Macroautophagy →	+0.058	+0.093	<.001	.002	3	11
LARGE_INTESTINE	Spliceosomal tri-snRNP complex assembly →	+0.076	+0.072	.001	<.001	3	9
LARGE_INTESTINE	Spliceosomal complex assembly →	+0.057	+0.077	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Termination of RNA polymerase II transcription →	+0.106	+0.101	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,648 associations by consensus.

Process utilizing autophagic mechanism by POU4F3 expression — STOMACH

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