POU4F2

Across TCGA patient cohorts, POU4F2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,637 significant associations in total. STAD shows the largest number of these associations.

The most reproducible POU4F2-associated GO terms across cancer lineages are Cellular senescence, Protein localization to chromosome, and Peptidyl-lysine modification. Each is linked with POU4F2 in more than 10 cancer types. Because this analysis shows association rather than direction, both POU4F2-to-partner and partner-to-POU4F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular senescence grouped by POU4F2-low versus POU4F2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU4F2→partner) and Y-score (partner→POU4F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular senescence →	+0.049	+0.022	<.001	.002	3	10
SCLC	Protein localization to chromosome →	+0.060	+0.565	.004	<.001	3	10
STAD	Peptidyl-lysine modification →	+0.045	+0.024	<.001	.001	2	11
STAD	Cell cycle G1/S phase transition →	+0.059	+0.043	<.001	<.001	2	11
STAD	Positive regulation of mitotic cell cycle →	+0.059	+0.038	<.001	.004	2	11
STAD	Establishment of protein localization to chromosome →	+0.046	+0.027	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,637 associations by consensus.

Cellular senescence by POU4F2 expression — STAD

Explore this box plot interactively →