POU4F2

Across TCGA cell cohorts, POU4F2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,663 significant associations in total. BONE shows the largest number of these associations.

The most reproducible POU4F2-associated GO terms across cancer lineages are Regulation of nucleobase-containing compound transport, DNA replication-dependent chromatin disassembly, and Positive regulation of nucleobase-containing compound transport. Each is linked with POU4F2 in more than 3 cancer types. Because this analysis shows association rather than direction, both POU4F2-to-partner and partner-to-POU4F2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleobase-containing compound transport grouped by POU4F2-low versus POU4F2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POU4F2→partner) and Y-score (partner→POU4F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of nucleobase-containing compound transport →	+0.064	+0.009	.001	.009	3	4
BONE	DNA replication-dependent chromatin disassembly →	+0.131	+1.009	<.001	.004	3	4
BONE	Positive regulation of nucleobase-containing compound transport →	+0.142	+1.116	<.001	.005	3	3
BONE	Taxis →	-0.104	-1.128	<.001	.002	3	3
BONE	Chemotaxis →	-0.104	-1.128	<.001	.002	3	3
PANCREAS	Aromatic amino acid metabolic process →	-0.155	-0.004	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,663 associations by consensus.

Regulation of nucleobase-containing compound transport by POU4F2 expression — BLOOD_Lymphoma

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