Across TCGA patient cohorts, POU3F4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,145 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POU3F4-associated genes across cancer lineages are EIF4A1P11, CYTH4, and CRYBB2P1. Each is linked with POU3F4 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F4-to-partner and partner-to-POU3F4 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F4→partner) and Y-score (partner→POU3F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EIF4A1P11 →	+0.810	+1.339	<.001	.001	3	2
GBM	CYTH4 →	-0.755	-0.952	.001	<.001	3	1
GBM	CRYBB2P1 →	+0.331	+0.856	.009	.001	3	1
GBM	HPS4 →	+0.311	+0.741	.004	.003	3	1
GBM	GCAT →	+0.778	+1.283	<.001	<.001	3	1
GBM	CRYBB1 →	-0.556	-0.618	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,145 associations by consensus.

Exploration

POU3F4 survival (RNA) · tumor vs normal (RNA) · all POU3F4 data types