Across TCGA cell cohorts, POU3F4 RNA expression is significantly associated with the mutation status of many other genes, with 72 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible POU3F4-associated genes across cancer lineages are PRSS55, UNC79, and ABCA13. Each is linked with POU3F4 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F4-to-partner and partner-to-POU3F4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F4→partner) and Y-score (partner→POU3F4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	PRSS55 →	+4.930	+0.454	.008	<.001	3	2
KIDNEY	UNC79 →	+5.000	+0.006	.005	<.001	3	2
KIDNEY	ABCA13 →	+5.000	+0.006	.005	<.001	3	2
BLOOD_Myeloma	TTC6 →	+3.906	+0.098	.009	<.001	3	1
BLOOD_Myeloma	BAZ2A →	+3.906	+0.098	.009	<.001	3	1
SOFT_TISSUE	HERC2 →	+4.930	+0.454	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

Exploration

POU3F4 survival (RNA) · tumor vs normal (RNA) · all POU3F4 data types