Across TCGA patient cohorts, POU3F3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,986 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible POU3F3-associated genes across cancer lineages are NCF4, ACTR5, and ADNP2. Each is linked with POU3F3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F3-to-partner and partner-to-POU3F3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F3→partner) and Y-score (partner→POU3F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NCF4 →	-0.750	-0.488	<.001	<.001	3	2
CCRCC	ACTR5 →	+0.328	+0.359	<.001	<.001	3	2
CCRCC	ADNP2 →	+0.337	+0.308	<.001	<.001	3	2
GBM	MAP3K8 →	-0.826	-0.428	.001	<.001	3	2
CCRCC	DHX15 →	+0.277	+0.332	<.001	.002	3	2
GBM	IL10RA →	-0.839	-0.433	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,986 associations by consensus.

Exploration

POU3F3 survival (RNA) · tumor vs normal (RNA) · all POU3F3 data types