POU3F3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POU3F3 mutation is significantly associated with the RNA expression of many other genes, with 376 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POU3F3-associated genes across cancer lineages are VN1R6P, NPAP1P2, and PLCE1P1. Each is linked with POU3F3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F3-to-partner and partner-to-POU3F3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F3→partner) and Y-score (partner→POU3F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAVN1R6P →+0.047+5.038.008.00932
HNSCNPAP1P2 →+0.084+4.508<.001.00532
LUADPLCE1P1 →+0.228+7.924<.001<.00132
BRCARNU6-532P →+0.258+8.471<.001.00532
LUSCRN7SL634P →+0.234+4.475<.001.00532
SKCMKCNK18 →+0.046+5.513<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 376 associations by consensus.

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