POU3F3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POU3F3 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POU3F3-associated genes across cancer lineages are Lck, Annexin-1, and eIF4E. Each is linked with POU3F3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POU3F3-to-partner and partner-to-POU3F3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F3→partner) and Y-score (partner→POU3F3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECLck →+0.251+3.000.030.03732
UCECAnnexin-1 →+0.632+3.000.037.03732
UCECeIF4E →+0.243+3.000.046.03722
UCEC4E-BP1 →+0.429+3.000.006.03731
UCECMSH2 →-0.489-3.000<.001.03721
UCECAR →-0.502-3.000.020.03712
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

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