Across TCGA patient cohorts, POU3F2 mutation is significantly associated with the RNA expression of many other genes, with 3,241 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POU3F2-associated genes across cancer lineages are RNA5SP512, RN7SL134P, and MIR6889. Each is linked with POU3F2 in more than 2 cancer types. Because this analysis shows association rather than direction, both POU3F2-to-partner and partner-to-POU3F2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU3F2→partner) and Y-score (partner→POU3F2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	RNA5SP512 →	+0.756	+4.730	<.001	.003	3	3
READ	RN7SL134P →	+0.283	+5.179	<.001	.001	3	3
CESC	MIR6889 →	+0.819	+3.667	.003	.007	3	2
CESC	OR1A1 →	+0.032	+4.144	<.001	.009	3	2
READ	PGBD4P2 →	+0.121	+5.257	<.001	.002	3	2
UCEC	COX15 →	+0.451	+3.860	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,241 associations by consensus.

Exploration

POU3F2 survival (RNA) · tumor vs normal (RNA) · all POU3F2 data types