POU2F1

Across TCGA patient cohorts, POU2F1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,479 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POU2F1-associated genes across cancer lineages are USP21, POGZ, and CLK2. Each is linked with POU2F1 in more than 5 cancer types. Because this analysis shows association rather than direction, both POU2F1-to-partner and partner-to-POU2F1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POU2F1 versus USP21 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU2F1→partner) and Y-score (partner→POU2F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP21 →	+0.571	+0.282	<.001	<.001	3	6
HNSC	POGZ →	+0.774	+0.281	<.001	<.001	3	6
UCEC	CLK2 →	+0.575	+0.299	<.001	<.001	3	6
HNSC	UTP25 →	+0.647	+0.299	<.001	<.001	3	6
UCEC	TADA1 →	+0.629	+0.344	<.001	<.001	3	6
UCEC	SNRPE →	+0.853	+0.208	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,479 associations by consensus.

POU2F1 vs USP21 — UCEC

Explore this scatter interactively →