POU1F1

Across TCGA patient cohorts, POU1F1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,356 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POU1F1-associated genes across cancer lineages are POGLUT2, RNF2, and IGHJ2. Each is linked with POU1F1 in more than 2 cancer types. Because this analysis shows association rather than direction, both POU1F1-to-partner and partner-to-POU1F1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POU1F1 versus POGLUT2 in UCEC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POU1F1→partner) and Y-score (partner→POU1F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	POGLUT2 →	-0.985	-0.851	<.001	.002	3	3
LSCC	RNF2 →	-0.295	-0.434	.008	.006	3	3
HNSC	IGHJ2 →	+1.745	+0.705	.003	.002	3	3
GBM	LINC00426 →	+0.399	+0.464	<.001	.008	3	3
LSCC	ALMS1 →	-0.500	-0.650	.001	.005	3	3
LSCC	DESI2 →	-0.433	-0.569	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,356 associations by consensus.

POU1F1 vs POGLUT2 — UCEC

Explore this scatter interactively →