POTEG

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POTEG mutation is significantly associated with the RNA expression of many other genes, with 236 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible POTEG-associated genes across cancer lineages are RN7SL98P, RN7SL808P, and RNU6-1213P. Each is linked with POTEG in more than 1 cancer types. Because this analysis shows association rather than direction, both POTEG-to-partner and partner-to-POTEG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEG→partner) and Y-score (partner→POTEG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL98P →+0.188+3.845<.001<.00132
UCECRN7SL808P →+0.086+4.292<.001.00632
UCECRNU6-1213P →+0.296+4.292<.001.00632
SKCMPGAM1 →+0.637+3.353.003.00532
SKCMRNA5SP451 →+0.093+4.315<.001.00532
SKCMACTBP13 →+0.031+2.788.006.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 236 associations by consensus.

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