Across TCGA patient cohorts, POTEE RNA expression is significantly associated with the protein abundance of many other proteins, with 8,997 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible POTEE-associated proteins across cancer lineages are TOP2A, TK1, and TOP2A_S1377. Each is linked with POTEE in more than 3 cancer types. Because this analysis shows association rather than direction, both POTEE-to-partner and partner-to-POTEE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEE→partner) and Y-score (partner→POTEE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOP2A →	+1.106	+0.807	<.001	.002	3	4
LSCC	TK1 →	+0.619	+2.122	<.001	<.001	3	3
OV	TOP2A_S1377 →	+0.998	+0.592	.001	.003	3	3
OV	PLOD1 →	+0.538	+0.715	.001	<.001	3	3
OV	PLOD2 →	+0.731	+0.593	.002	.008	3	3
LUAD	ZNF687_S1211 →	+0.682	+0.903	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,997 associations by consensus.

Exploration

POTEE survival (RNA) · tumor vs normal (RNA) · all POTEE data types