POTEB3

Across TCGA patient cohorts, POTEB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,659 significant associations in total. STAD shows the largest number of these associations.

The most reproducible POTEB3-associated GO terms across cancer lineages are rRNA methylation, Mitochondrial respiratory chain complex assembly, and Regulation of exocytosis. Each is linked with POTEB3 in more than 5 cancer types. Because this analysis shows association rather than direction, both POTEB3-to-partner and partner-to-POTEB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA methylation grouped by POTEB3-low versus POTEB3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEB3→partner) and Y-score (partner→POTEB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	rRNA methylation →	+0.094	+0.020	<.001	<.001	3	6
STAD	Mitochondrial respiratory chain complex assembly →	+0.129	+0.012	<.001	<.001	3	6
STAD	Regulation of exocytosis →	+0.074	+0.012	<.001	<.001	3	5
STAD	Insulin secretion →	+0.071	+0.016	<.001	<.001	3	5
STAD	Negative regulation of cellular catabolic process →	+0.099	+0.011	<.001	<.001	3	5
STAD	Mitochondrial translation →	+0.141	+0.022	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,659 associations by consensus.

rRNA methylation by POTEB3 expression — STAD

Explore this box plot interactively →