POTEB2

Across TCGA cell cohorts, POTEB2 RNA expression is significantly associated with the mutation status of many other genes, with 81 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POTEB2-associated genes across cancer lineages are FAM171A2, MT-ND4, and SEC14L1. Each is linked with POTEB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both POTEB2-to-partner and partner-to-POTEB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM171A2 grouped by POTEB2-low versus POTEB2-high in STOMACH.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEB2→partner) and Y-score (partner→POTEB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	FAM171A2 →	+4.285	+0.005	.007	<.001	3	2
STOMACH	MT-ND4 →	+4.285	+0.005	.007	<.001	3	2
LUNG_SCLC	SEC14L1 →	+5.029	+0.012	.006	<.001	3	2
LUNG_SCLC	RETSAT →	+5.029	+0.012	.006	<.001	3	2
BLOOD_Myeloma	ARHGAP29 →	+4.754	+0.702	<.001	<.001	3	1
BLOOD_Myeloma	ITSN1 →	+4.754	+0.702	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

FAM171A2 by POTEB2 expression — STOMACH

Explore this box plot interactively →