POTEB2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, POTEB2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of POTEB2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where POTEB2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types POTEB2 is over-expressed in tumor.

BRCA are the cancer types where POTEB2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in POTEB2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllAll+0.002.0442view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

POTEB2–BRCA

Tumor-vs-normal expression box plot for POTEB2 RNA in BRCA.

Open the BRCA breakdown →

Exploration