Across TCGA patient cohorts, POTEA RNA expression is significantly associated with the go_rna of many other GO terms, with 5,857 significant associations in total. STAD shows the largest number of these associations.

The most reproducible POTEA-associated GO terms across cancer lineages are Cellular respiration, Positive regulation of telomere maintenance via telomere lengthening, and Membrane fusion. Each is linked with POTEA in more than 8 cancer types. Because this analysis shows association rather than direction, both POTEA-to-partner and partner-to-POTEA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POTEA→partner) and Y-score (partner→POTEA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cellular respiration →	+0.086	+0.062	<.001	<.001	3	9
STAD	Positive regulation of telomere maintenance via telomere lengthening →	+0.074	+0.051	<.001	<.001	3	8
STAD	Membrane fusion →	+0.058	+0.064	<.001	<.001	3	8
STAD	Base-excision repair, gap-filling →	+0.070	+0.082	<.001	<.001	3	8
STAD	Intracellular protein transmembrane transport →	+0.077	+0.069	<.001	<.001	3	8
STAD	DNA conformation change →	+0.073	+0.059	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,857 associations by consensus.

Exploration

POTEA survival (RNA) · tumor vs normal (RNA) · all POTEA data types