POSTN

Across TCGA cell cohorts, POSTN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,664 significant associations in total. BONE shows the largest number of these associations.

The most reproducible POSTN-associated GO terms across cancer lineages are Negative regulation of endodermal cell differentiation, Golgi vesicle transport, and Protein folding. Each is linked with POSTN in more than 9 cancer types. Because this analysis shows association rather than direction, both POSTN-to-partner and partner-to-POSTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of endodermal cell differentiation grouped by POSTN-low versus POSTN-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POSTN→partner) and Y-score (partner→POSTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of endodermal cell differentiation →	+1.357	+2.483	<.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.043	+1.074	.002	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Protein folding →	+0.080	+1.495	<.001	.002	3	8
SKIN	Negative regulation of osteoclast development →	+0.978	+2.313	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Elastic fiber assembly →	+0.745	+1.387	.003	.006	3	8
BONE	Positive regulation of protein exit from endoplasmic reticulum →	+0.121	+3.728	.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,664 associations by consensus.

Negative regulation of endodermal cell differentiation by POSTN expression — OVARY

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