POP7

Across TCGA patient cohorts, POP7 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POP7-associated genes across cancer lineages are C2orf69P4, VTRNA3-1P, and RNA5SP359. Each is linked with POP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both POP7-to-partner and partner-to-POP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C2orf69P4 grouped by POP7-low versus POP7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POP7→partner) and Y-score (partner→POP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C2orf69P4 →	+0.084	+7.741	<.001	.009	3	2
LUAD	VTRNA3-1P →	+0.392	+5.554	<.001	.004	3	1
LUAD	RNA5SP359 →	+0.440	+4.990	<.001	.009	3	1
LUAD	RNU6-207P →	+0.493	+5.343	<.001	.006	3	1
LUAD	RNU6ATAC15P →	+0.864	+5.481	<.001	.005	3	1
LUAD	LINC01040 →	+1.121	+5.343	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

C2orf69P4 by POP7 expression — COAD

Explore this box plot interactively →