POP7

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POP7 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POP7-associated genes across cancer lineages are Class-switched memory B-cells. Each is linked with POP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both POP7-to-partner and partner-to-POP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Class-switched memory B-cells grouped by POP7-low versus POP7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POP7→partner) and Y-score (partner→POP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECClass-switched memory B-cells →-0.063-3.169.044.02011
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Class-switched memory B-cells by POP7 expression — UCEC

Box plot of Class-switched memory B-cells in POP7-low vs POP7-high samples in UCEC.

Explore this box plot interactively →

Exploration