PON3

Across TCGA cell cohorts, PON3 RNA expression is significantly associated with the RNA expression of many other genes, with 3,534 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PON3-associated genes across cancer lineages are PON1, KIF13B, and PON2. Each is linked with PON3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PON3-to-partner and partner-to-PON3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PON3 versus PON1 in LIVER, with a Pearson correlation of 0.53.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PON3→partner) and Y-score (partner→PON3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	PON1 →	+1.412	+3.806	<.001	<.001	3	7
LIVER	KIF13B →	+2.116	+3.574	<.001	<.001	3	5
LIVER	PON2 →	+1.332	+3.027	<.001	<.001	3	4
LIVER	FRK →	+1.390	+2.982	<.001	<.001	3	4
LUNG_SCLC	LYPD5 →	+1.141	+1.562	.001	.005	2	4
PANCREAS	C17orf107 →	+0.608	+1.673	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,534 associations by consensus.

PON3 vs PON1 — LIVER

Explore this scatter interactively →