POMT2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POMT2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,617 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POMT2-associated genes across cancer lineages are TNFRSF10A, ZNF773, and SLC39A9. Each is linked with POMT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both POMT2-to-partner and partner-to-POMT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POMT2 versus TNFRSF10A in HNSC, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMT2→partner) and Y-score (partner→POMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCTNFRSF10A →-1.406-1.487.003.00133
BRCAZNF773 →+1.047+0.864<.001.00133
LUADSLC39A9 →+0.611+0.651<.001<.00133
BRCACLBA1 →+1.318+0.872.002<.00133
GBMOR52H1 →+0.607+0.409<.001<.00133
BRCAMTA1 →+1.125+1.181.004.00533
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,617 associations by consensus.

POMT2 vs TNFRSF10A — HNSC

Per-sample scatter of POMT2 vs TNFRSF10A in HNSC (Pearson r = -0.62).

Explore this scatter interactively →

Exploration