POMT2

Across TCGA cell cohorts, POMT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,940 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible POMT2-associated GO terms across cancer lineages are Regulation of mRNA splicing, via spliceosome, Microtubule nucleation, and RNA export from nucleus. Each is linked with POMT2 in more than 16 cancer types. Because this analysis shows association rather than direction, both POMT2-to-partner and partner-to-POMT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA splicing, via spliceosome grouped by POMT2-low versus POMT2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POMT2→partner) and Y-score (partner→POMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of mRNA splicing, via spliceosome →	+0.093	+0.699	.004	.002	3	17
STOMACH	Microtubule nucleation →	+0.128	+1.027	<.001	<.001	2	17
OESOPHAGUS	RNA export from nucleus →	+0.156	+0.817	<.001	.009	3	15
STOMACH	Heterochromatin organization →	+0.060	+0.645	<.001	<.001	3	15
OESOPHAGUS	mRNA alternative polyadenylation →	+0.129	+0.887	.006	.008	3	15
URINARY_TRACT	Negative regulation of RNA splicing →	+0.098	+0.700	<.001	.004	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,940 associations by consensus.

Regulation of mRNA splicing, via spliceosome by POMT2 expression — STOMACH

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