POMT1

Across TCGA patient cohorts, POMT1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,624 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POMT1-associated genes across cancer lineages are DNAL1, NBL1, and DENND2D. Each is linked with POMT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both POMT1-to-partner and partner-to-POMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POMT1 versus DNAL1 in HNSC, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMT1→partner) and Y-score (partner→POMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DNAL1 →	+0.779	+1.050	.002	<.001	3	3
UCEC	NBL1 →	-1.044	-0.573	<.001	.001	3	3
HNSC	DENND2D →	-1.021	-0.638	<.001	<.001	3	3
HNSC	IGLV3-9 →	-3.252	-0.713	.003	.005	3	3
HNSC	LRP2BP →	+0.906	+0.923	.001	<.001	3	3
HNSC	NOXRED1 →	+0.516	+0.723	.005	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,624 associations by consensus.

POMT1 vs DNAL1 — HNSC

Explore this scatter interactively →