POMP

Across TCGA patient cohorts, POMP RNA expression is significantly associated with the protein abundance of many other proteins, with 9,680 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POMP-associated proteins across cancer lineages are HSPH1, SPRYD7, and NUBPL. Each is linked with POMP in more than 6 cancer types. Because this analysis shows association rather than direction, both POMP-to-partner and partner-to-POMP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POMP versus HSPH1 in BRCA, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POMP→partner) and Y-score (partner→POMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSPH1 →	+0.525	+0.710	<.001	<.001	3	7
GBM	SPRYD7 →	+0.247	+0.285	<.001	.004	3	4
BRCA	NUBPL →	-0.545	-0.448	<.001	<.001	3	4
BRCA	XPO4 →	+0.205	+0.375	.001	.002	3	4
OV	CCDC6_S52 →	+0.800	+0.561	<.001	<.001	3	4
OV	TBC1D15_S70 →	-0.874	-0.788	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,680 associations by consensus.

POMP vs HSPH1 — BRCA

Explore this scatter interactively →