Across TCGA patient cohorts, POMK protein abundance is significantly associated with the RNA expression of many other genes, with 15,382 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POMK-associated genes across cancer lineages are FGD3, PLD4, and CHML. Each is linked with POMK in more than 5 cancer types. Because this analysis shows association rather than direction, both POMK-to-partner and partner-to-POMK results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POMK→partner) and Y-score (partner→POMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FGD3 →	-0.949	-0.343	<.001	<.001	3	6
UCEC	PLD4 →	-0.740	-0.540	<.001	<.001	3	6
LUAD	CHML →	+0.955	+0.379	<.001	<.001	3	6
BRCA	TTK →	+1.106	+0.507	<.001	<.001	3	5
BRCA	CENPA →	+0.928	+0.398	<.001	<.001	3	5
BRCA	MAN1C1 →	-0.854	-0.545	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,382 associations by consensus.

Exploration

POMK survival (RNA) · tumor vs normal (RNA) · all POMK data types