Across TCGA pan-cancer cohorts, POM121L14P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of POM121L14P’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where POM121L14P RNA is repressed in tumor relative to normal tissue. In most cancer types POM121L14P is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.
THCA and KICH are the cancer types where POM121L14P tumor–normal differential expression is most reproducible.