POM121L10P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POM121L10P mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POM121L10P-associated genes across cancer lineages are SPDYE8, DEFT1P, and RNU6ATAC19P. Each is linked with POM121L10P in more than 1 cancer types. Because this analysis shows association rather than direction, both POM121L10P-to-partner and partner-to-POM121L10P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121L10P→partner) and Y-score (partner→POM121L10P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASPDYE8 →+0.019+8.471<.001.00531
BRCADEFT1P →+0.952+8.055<.001.00731
BRCARNU6ATAC19P →+0.729+7.731<.001.00931
BRCAGPM6BP1 →+0.268+8.055<.001.00731
BRCAPRYP2 →+0.089+7.731<.001.00931
BRCARNA5SP518 →+0.313+8.055<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

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