POM121C

Across TCGA pan-cancer cohorts, POM121C mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated POM121C data layer compared with 25 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher POM121C mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated POM121C expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, CCRCC, and HNSC are the cancer types where POM121C mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	II,III,IV	1.000	0.862	.004	35	view →
CCRCC	OS	Quartile	All	0.850	1.000	.043	4	view →
HNSC	DFS	Median	All	0.687	0.842	.019	4	view →
LSCC	DFS	Tertile	III,IV	1.000	0.795	.036	2	view →
GBM	OS	Median	All	0.423	0.274	.049	1	view →
PDAC	OS	Median	II,III,IV	0.742	0.381	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

POM121C–LUAD (OS)

Open the LUAD breakdown →