POM121C

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POM121C RNA expression is significantly associated with the protein abundance of many other proteins, with 13,086 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POM121C-associated proteins across cancer lineages are GTF2I, MEPCE, and WDR5. Each is linked with POM121C in more than 6 cancer types. Because this analysis shows association rather than direction, both POM121C-to-partner and partner-to-POM121C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POM121C versus GTF2I in LSCC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121C→partner) and Y-score (partner→POM121C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCGTF2I →+0.386+0.577<.001<.00137
LSCCMEPCE →+0.289+0.567<.001<.00136
LSCCWDR5 →+0.226+0.450<.001<.00135
LSCCFOXK1 →+0.375+0.707<.001<.00135
LSCCDHX9 →+0.207+0.501<.001<.00135
LSCCZC3HC1 →+0.169+0.465.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,086 associations by consensus.

POM121C vs GTF2I — LSCC

Per-sample scatter of POM121C vs GTF2I in LSCC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration