POM121C

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, POM121C protein abundance is significantly associated with the RNA expression of many other genes, with 9,095 significant associations in total. GBM shows the largest number of these associations.

The most reproducible POM121C-associated genes across cancer lineages are FBL, PTCD1, and STAG3L4. Each is linked with POM121C in more than 3 cancer types. Because this analysis shows association rather than direction, both POM121C-to-partner and partner-to-POM121C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POM121C versus FBL in HNSC, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121C→partner) and Y-score (partner→POM121C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCFBL →+0.864+0.211.001.00433
LSCCPTCD1 →+0.380+0.201<.001<.00133
LSCCSTAG3L4 →+0.541+0.222<.001.00233
LSCCFAHD2A →+0.484+0.203<.001.00533
GBMSRGN →-0.928-0.210<.001.00433
LSCCMED20 →+0.563+0.193.003.00833
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,095 associations by consensus.

POM121C vs FBL — HNSC

Per-sample scatter of POM121C vs FBL in HNSC (Pearson r = 0.24).

Explore this scatter interactively →

Exploration