POM121C

Across TCGA cell cohorts, POM121C RNA expression is significantly associated with the go_rna of many other GO terms, with 5,053 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POM121C-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, Epigenetic regulation of gene expression, and Regulation of nucleotide-excision repair. Each is linked with POM121C in more than 17 cancer types. Because this analysis shows association rather than direction, both POM121C-to-partner and partner-to-POM121C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of isotype switching to IgG isotypes grouped by POM121C-low versus POM121C-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POM121C→partner) and Y-score (partner→POM121C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of isotype switching to IgG isotypes →	+0.152	+0.848	.002	.003	3	18
BONE	Epigenetic regulation of gene expression →	+0.072	+0.886	<.001	<.001	3	17
BONE	Regulation of nucleotide-excision repair →	+0.124	+0.927	<.001	<.001	3	16
BONE	Nucleic acid transport →	+0.146	+1.031	<.001	<.001	3	16
BONE	RNA transport →	+0.146	+1.031	<.001	<.001	3	16
BONE	Positive regulation of DNA recombination →	+0.128	+0.948	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,053 associations by consensus.

Positive regulation of isotype switching to IgG isotypes by POM121C expression — BONE

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