POLR3H

Across TCGA patient cohorts, POLR3H RNA expression is significantly associated with the mutation status of many other genes, with 10,773 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POLR3H-associated genes across cancer lineages are TP53, OBSCN, and MUC4. Each is linked with POLR3H in more than 3 cancer types. Because this analysis shows association rather than direction, both POLR3H-to-partner and partner-to-POLR3H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by POLR3H-low versus POLR3H-high in LIHC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3H→partner) and Y-score (partner→POLR3H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	TP53 →	+0.997	+0.269	<.001	<.001	3	4
LIHC	OBSCN →	+2.201	+0.281	.001	.002	3	4
STAD	MUC4 →	+3.254	+0.346	.007	.004	3	4
UCEC	HSPG2 →	+1.301	+0.315	<.001	<.001	3	4
LIHC	ZFHX4 →	+3.345	+0.417	.005	.005	2	4
COAD	PTPRZ1 →	+2.820	+0.283	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,773 associations by consensus.

TP53 by POLR3H expression — LIHC

Explore this box plot interactively →