POLR3H

Across TCGA cell cohorts, POLR3H RNA expression is significantly associated with the go_rna of many other GO terms, with 4,593 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible POLR3H-associated GO terms across cancer lineages are DNA replication-dependent chromatin assembly, Protein localization to microtubule plus-end, and Protein localization to microtubule end. Each is linked with POLR3H in more than 15 cancer types. Because this analysis shows association rather than direction, both POLR3H-to-partner and partner-to-POLR3H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication-dependent chromatin assembly grouped by POLR3H-low versus POLR3H-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3H→partner) and Y-score (partner→POLR3H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA replication-dependent chromatin assembly →	+0.215	+0.993	<.001	<.001	3	16
BLOOD_Lymphoma	Protein localization to microtubule plus-end →	+0.165	+0.944	<.001	<.001	2	15
BLOOD_Lymphoma	Protein localization to microtubule end →	+0.165	+0.944	<.001	<.001	2	15
URINARY_TRACT	Termination of RNA polymerase III transcription →	+0.120	+1.192	<.001	<.001	3	14
BONE	Regulation of DNA-templated DNA replication →	+0.116	+0.786	.003	<.001	3	14
BONE	Mitotic chromosome condensation →	+0.140	+0.723	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,593 associations by consensus.

DNA replication-dependent chromatin assembly by POLR3H expression — BONE

Explore this box plot interactively →