POLR3GP2

Across TCGA patient cohorts, POLR3GP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,595 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POLR3GP2-associated GO terms across cancer lineages are Negative regulation of alpha-beta T cell activation, Cranial nerve development, and Cellular response to decreased oxygen levels. Each is linked with POLR3GP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both POLR3GP2-to-partner and partner-to-POLR3GP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of alpha-beta T cell activation grouped by POLR3GP2-low versus POLR3GP2-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3GP2→partner) and Y-score (partner→POLR3GP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Negative regulation of alpha-beta T cell activation →	+0.051	+0.026	<.001	.001	3	9
KIRP	Cranial nerve development →	+0.056	+0.035	<.001	<.001	3	8
UCEC	Cellular response to decreased oxygen levels →	+0.054	+0.047	<.001	<.001	3	8
UCEC	Regulation of binding →	+0.064	+0.033	<.001	<.001	3	8
UCEC	Positive regulation of cell division →	+0.038	+0.029	<.001	<.001	3	8
ESCA	Cellular response to oxygen levels →	+0.062	+0.118	<.001	.002	1	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,595 associations by consensus.

Negative regulation of alpha-beta T cell activation by POLR3GP2 expression — UCEC

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