POLR3GP2

Across TCGA pan-cancer cohorts, POLR3GP2 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated POLR3GP2 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher POLR3GP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated POLR3GP2 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

THCA, KICH, and READ are the cancer types where POLR3GP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.901	0.980	<.001	96	view →
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
READ	DFS	Tertile	All	0.617	0.861	.006	72	view →
MESO	OS	Tertile	II,III,IV	0.226	0.581	.002	63	view →
UCEC	OS	Tertile	II,III,IV	0.117	0.547	.001	60	view →
KIRC	DFS	Tertile	IV	0.255	0.680	.001	48	view →
LIHC	OS	Tertile	All	0.162	0.709	.004	36	view →
HNSC	OS	Tertile	II,III,IV	0.165	0.441	.005	30	view →
LGG	DFS	Tertile	All	0.158	0.453	.009	21	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
ACC	DFS	Tertile	II,III,IV	0.242	0.724	.034	18	view →
LUSC	DFS	Tertile	III,IV	0.425	0.694	.004	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

POLR3GP2–THCA (OS)

Open the THCA breakdown →