POLR3GP1

Across TCGA patient cohorts, POLR3GP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,934 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible POLR3GP1-associated GO terms across cancer lineages are Vacuolar transport, Regulation of RNA splicing, and Alternative mRNA splicing, via spliceosome. Each is linked with POLR3GP1 in more than 22 cancer types. Because this analysis shows association rather than direction, both POLR3GP1-to-partner and partner-to-POLR3GP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by POLR3GP1-low versus POLR3GP1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3GP1→partner) and Y-score (partner→POLR3GP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Vacuolar transport →	+0.059	+0.129	.003	.006	2	23
DLBC	Regulation of RNA splicing →	+0.065	+0.149	.001	.005	2	22
DLBC	Alternative mRNA splicing, via spliceosome →	+0.061	+0.157	<.001	.001	3	20
DLBC	Glycerolipid biosynthetic process →	+0.049	+0.122	.001	.001	3	20
DLBC	Translational elongation →	+0.054	+0.167	.004	.007	1	22
DLBC	Positive regulation of chromosome organization →	+0.067	+0.143	.001	.003	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,934 associations by consensus.

Vacuolar transport by POLR3GP1 expression — DLBC

Explore this box plot interactively →