POLR3G

Across TCGA pan-cancer cohorts, POLR3G Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated POLR3G data layer compared with 24 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher POLR3G Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated POLR3G expression acts as an unfavorable survival marker.

LUAD and GBM are the cancer types where POLR3G Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.171	0.835	<.001	24	view →
GBM	OS	Median	All	0.109	0.415	.032	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

POLR3G–LUAD (OS)

Open the LUAD breakdown →