POLR3F

Across TCGA patient cohorts, POLR3F RNA expression is significantly associated with the protein abundance of many other proteins, with 15,381 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR3F-associated proteins across cancer lineages are TRMT6, TRMT61A, and XRN2. Each is linked with POLR3F in more than 8 cancer types. Because this analysis shows association rather than direction, both POLR3F-to-partner and partner-to-POLR3F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3F versus TRMT6 in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3F→partner) and Y-score (partner→POLR3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRMT6 →	+0.393	+0.533	<.001	<.001	3	9
PDAC	TRMT61A →	+0.352	+0.284	.001	<.001	3	7
HNSC	XRN2 →	+0.240	+0.645	<.001	.007	2	8
HNSC	ESF1 →	+0.471	+0.612	<.001	.001	3	7
COAD	ZCCHC3 →	+0.663	+0.828	<.001	<.001	3	6
GBM	CENPB →	+0.251	+0.246	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,381 associations by consensus.

POLR3F vs TRMT6 — LSCC

Explore this scatter interactively →