POLR3F

Across TCGA patient cohorts, POLR3F protein abundance is significantly associated with the RNA expression of many other genes, with 11,907 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR3F-associated genes across cancer lineages are POLR3K, TFAP4, and FASTKD5. Each is linked with POLR3F in more than 5 cancer types. Because this analysis shows association rather than direction, both POLR3F-to-partner and partner-to-POLR3F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3F versus POLR3K in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3F→partner) and Y-score (partner→POLR3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	POLR3K →	+0.658	+0.222	<.001	<.001	3	6
LSCC	TFAP4 →	+0.564	+0.241	<.001	<.001	3	6
HNSC	FASTKD5 →	+0.751	+0.179	.001	.002	3	5
OV	PLAU →	-1.057	-0.220	<.001	.001	3	5
HNSC	LRPPRC →	+0.563	+0.222	<.001	.002	3	5
HNSC	CCDC138 →	+0.652	+0.238	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,907 associations by consensus.

POLR3F vs POLR3K — BRCA

Explore this scatter interactively →