POLR3F

Across TCGA patient cohorts, POLR3F mutation is significantly associated with the RNA expression of many other genes, with 2,202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POLR3F-associated genes across cancer lineages are FAM47A, MTCO3P16, and RNU6-1082P. Each is linked with POLR3F in more than 1 cancer types. Because this analysis shows association rather than direction, both POLR3F-to-partner and partner-to-POLR3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM47A grouped by POLR3F-low versus POLR3F-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3F→partner) and Y-score (partner→POLR3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	FAM47A →	+0.018	+5.306	.004	.006	3	2
COAD	MTCO3P16 →	+0.199	+5.893	<.001	.002	3	2
HNSC	RNU6-1082P →	+0.363	+5.124	<.001	.008	3	2
UCEC	RNU6-66P →	+0.270	+2.920	<.001	.008	3	2
UCEC	LINC01047 →	+0.138	+1.856	<.001	.006	3	2
UCEC	MIR4535 →	+0.402	+3.462	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,202 associations by consensus.

FAM47A by POLR3F expression — CESC

Explore this box plot interactively →