POLR3F

Across TCGA cell cohorts, POLR3F RNA expression is significantly associated with the go_rna of many other GO terms, with 2,979 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible POLR3F-associated GO terms across cancer lineages are DNA-templated transcription termination, Transcription by RNA polymerase III, and Regulation of chromosome segregation. Each is linked with POLR3F in more than 14 cancer types. Because this analysis shows association rather than direction, both POLR3F-to-partner and partner-to-POLR3F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription termination grouped by POLR3F-low versus POLR3F-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3F→partner) and Y-score (partner→POLR3F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DNA-templated transcription termination →	+0.084	+0.679	<.001	<.001	3	15
LUNG_NSCLC_LUAD	Transcription by RNA polymerase III →	+0.065	+0.712	<.001	<.001	3	13
LIVER	Regulation of chromosome segregation →	+0.103	+0.621	<.001	.002	3	13
OVARY	Nuclear division →	+0.060	+0.577	<.001	.005	3	12
LUNG_NSCLC_LUSC	mRNA export from nucleus →	+0.099	+1.055	.001	.001	3	12
LIVER	Regulation of metaphase/anaphase transition of cell cycle →	+0.108	+0.586	<.001	.004	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,979 associations by consensus.

DNA-templated transcription termination by POLR3F expression — LARGE_INTESTINE

Explore this box plot interactively →