POLR3E

Across TCGA patient cohorts, POLR3E RNA expression is significantly associated with the protein abundance of many other proteins, with 12,820 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible POLR3E-associated proteins across cancer lineages are PARN, USP7, and POLR3A. Each is linked with POLR3E in more than 8 cancer types. Because this analysis shows association rather than direction, both POLR3E-to-partner and partner-to-POLR3E results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, POLR3E versus PARN in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (POLR3E→partner) and Y-score (partner→POLR3E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PARN →	+0.295	+0.431	<.001	<.001	3	9
OV	USP7 →	+0.240	+0.350	<.001	.001	3	7
LSCC	POLR3A →	+0.316	+0.525	<.001	<.001	3	7
BRCA	DCTPP1 →	+0.544	+0.502	<.001	<.001	3	6
OV	NFATC2IP →	+0.334	+0.423	.001	.008	3	6
OV	POLR3D →	+0.370	+0.629	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,820 associations by consensus.

POLR3E vs PARN — OV

Explore this scatter interactively →